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| CRISPR/CAS9-MEDIATED CORRECTION OF MITF HOMOZYGOUS POINT MUTATION IN A WAARDENBURG SYNDROME 2A PIG MODEL 期刊论文
Molecular Therapy-nucleic Acids, 2021, 卷号: 24, 页码: 986-999
作者: Yao Jing; Wang Yu; Cao Chunwei; Song Ruigao; Bi Dengfeng; Zhang Hongyong; Li Yongshun; Qin Guosong; Hou Naipeng; Zhang Nan; Zhang Jin; Guo Weiwei; Yang Shiming; Wang Yanfang; Zhao Jianguo
 Adobe PDF(3157Kb) |  收藏 | 浏览/下载：235/116 | 提交时间：2023/04/17 |
| A pig model carrying heterozygous point mutation of NCSTN simulates familial acne inversa and reveals dysregulated cholesterol biosynthesis via the Notch-pAMPK-HMGCR pathway 期刊论文
SCIENCE BULLETIN, 2021, 卷号: 66, 期号: 23, 页码: 2343-2346
作者: Song RG(宋瑞高); Liu KQ(刘克强); Wang Y(王煜); Qin GS(秦国嵩); Xiao M(肖萌); Liu YP(刘雅萍); Yang J(杨俊); Zong RJ(宗若君); Yan XH(闫星彗); Zheng QT(郑千涛); Zhang HY(张洪勇); Hou NP(侯乃鹏); Yao J(姚婧); Wang X(王霄); Wang YF(王彦芳); Zhao JG(赵建国); Zhang X(张学)
Adobe PDF(1650Kb) | 收藏 | 浏览/下载：283/122 | 提交时间：2023/04/17 |
| An exonic splicing enhancer mutation in DUOX2 causes aberrant alternative splicing and severe congenital hypothyroidism in Bama pigs 期刊论文
Disease Models & Mechanisms, 2019, 卷号: 12, 期号: 1, 页码: 1-8
作者: Cao CW(曹春伟); Zhang Y(张颖); Jia QT(贾启涛); Wang X(王霄); Zheng QT(郑千涛); Zhang HY(张洪勇); Song RG(宋瑞高); Li YS(李永顺); Luo AL(罗霭玲); Hong QL(洪潜龙); Qin GS(秦国嵩); Yao J(姚婧); Zhang N(张楠); Wang YF(王彥芳); Wang HM(王红梅); Zhou Q(周琪); Zhao JG(赵建国)
Adobe PDF(1234Kb) | 收藏 | 浏览/下载：377/136 | 提交时间：2020/11/17 |
| A novel porcine model reproduces human oculocutaneous albinism type II 期刊论文
Cell Discovery, 2019, 卷号: 5, 期号: 1, 页码: 1-3
作者: Zhang Y(张颖); Hong QL(洪潜龙); Cao CW(曹春伟); Yang LZ(杨丽珠); Li YS(李永顺); Hai T(海棠); Zhang HY(张洪勇); Zhou Q(周琪); Sui RF(睢瑞芳); Zhao JG(赵建国)
Adobe PDF(766Kb) | 收藏 | 浏览/下载：368/145 | 提交时间：2020/11/17 |
| A harlequin ichthyosis pig model with a novel ABCA12mutation can be rescued by acitretin treatment 期刊论文
Journal of Molecular Cell Biology, 2019, 卷号: 11, 期号: 12, 页码: 1029-1041
作者: Wang X(王霄); Cao CW(曹春伟); Li YS(李永顺); Hai T(海棠); Jia QT(贾启涛); Zhang Y(张颖); Zheng QT(郑千涛); Yao J(姚婧); Qin GS(秦国嵩); Zhang HY(张洪勇); Song RG(宋瑞高); Wang YF(王彥芳); Guanghou Shui; Sin Man Lam; Liu ZH(刘忠华); Wei H(魏泓); Meng AM(孟安明); Zhou Q(周琪); Zhao JG(赵建国)
 浏览 |  Adobe PDF(104496Kb) | 收藏 | 浏览/下载：358/80 | 提交时间：2020/11/17 |
| Rescuing ocular development in an anophthalmic pig by blastocyst complementation 期刊论文
EMBO Molecular Medicine, 2018, 期号: doi: 10.15252/emmm.201808861, 页码: 10; e8861：1-12
作者: Zhang HY(张洪勇); Huang JJ(黄娇娇); Li ZC(李泽辰); Qin GS(秦国嵩); Zhang N(张楠); Hai T(海棠); Hong QL(洪潜龙); Zheng QT(郑千涛); Zhang Y(张颖); Song RG(宋瑞高); Yao J(姚婧); Cao CW(曹春伟); Zhao JG(赵建国); Zhou Q(周琪)
Adobe PDF(3390Kb) | 收藏 | 浏览/下载：488/185 | 提交时间：2019/10/14 |
| Pilot Study of Large-Scale Production of Mutant Pigs by ENU Mutagenesis 期刊论文
eLife, 2017, 卷号: 6, 页码: Article No. e26248
作者: Hai T(海棠); Cao CW(曹春伟); Hai-Tao Shang; Wei-Wei Guo; Yan-Shuang Mu; Yang SL(杨述林); Zhang Y(张颖); Zheng QT(郑千涛); Tao Zhang; Wang XL(王宪龙); Yu Liu; Qing-Ran Kong; Li K(李奎); Wang DY(王大愚); Qi M(祁蒙); Hong QL(洪潜龙); Zhang R(张蕊); Wang XP(王秀鹏); Jia QT(贾启涛); Wang X(王霄); Qin GS(秦国嵩); Yong-Shun Li; Luo AL(罗霭玲); Wei-Wu Jin; Yao J(姚婧); Huang JJ(黄娇娇); Zhang HY(张洪勇); Li MH(李孟华); Xiang-Mo Xie; Xue-Juan Zheng; Ke-Nan Guo; Gu WW(顾为望); Ming Li; Yong Wang; Wang HM(王红梅); Yang SM(杨仕明); Liu ZH(刘忠华); Wei H(魏泓); Zhao JG(赵建国); Zhou Q(周琪); Meng AM(孟安明)
Adobe PDF(3521Kb) | 收藏 | 浏览/下载：671/227 | 提交时间：2018/07/09 |
| Reconstitution of UCP1 Using CRISPR/Cas9 in the White Adipose Tissue of Pigs Decreases Fat Deposition and Improves Thermogenic Capacity 期刊论文
PNAS, 2017, 卷号: 114, 期号: 45, 页码: E9474-E9482
作者: Zheng QT(郑千涛); Lin J(林骏); Huang JJ(黄娇娇); Zhang HY(张洪勇); Zhang R(张蕊); Xue-Ying Zhang; Cao CW(曹春伟); Catherine Hambly; Qin GS(秦国嵩); Yao J(姚婧); Song RG(宋瑞高); Jia QT(贾启涛); Wang X(王霄); Yong-Shun Li; Zhang N(张楠); Zheng-Yu Piao; Ye RC(叶荣财); John R.Speakman; Wang HM(王红梅); Zhou Q(周琪); Wang YF(王彦芳); Jin WZ(金万洙); Zhao JG(赵建国)
浏览 | Adobe PDF(1304Kb) | 收藏 | 浏览/下载：687/220 | 提交时间：2018/07/09 |
| Reconstitution of UCP1 Using CRISPR/Cas9 in the White Adipose Tissue of Pigs Decreases Fat Deposition and Improves Thermogenic Capacity 期刊论文
PNAS, 2017, 卷号: 114, 期号: 45, 页码: E9474-E9482
作者: Zheng QT(郑千涛); Lin J(林骏); Huang JJ(黄娇娇); Zhang HY(张洪勇); Zhang R(张蕊); Xue-Ying Zhang; Cao CW(曹春伟); Catherine Hambly; Qin GS(秦国嵩); Yao J(姚婧); Song RG(宋瑞高); Jia QT(贾启涛); Wang X(王霄); Yong-Shun Li; Zhang N(张楠); Zheng-Yu Piao; Ye RC(叶荣财); John R.Speakman; Wang HM(王红梅); Zhou Q(周琪); Wang YF(王彦芳); Jin WZ(金万洙); Zhao JG(赵建国)
浏览 | Adobe PDF(1304Kb) | 收藏 | 浏览/下载：545/217 | 提交时间：2018/07/09 |
| Creation of Miniature Pig Model of Human Waardenburg Syndrome Type 2A by ENU Mutagenesis 期刊论文
Human Genetics, 2017, 卷号: 136, 期号: 11-12, 页码: 1463-1475
作者: Hai T(海棠); Wei-Wei Guo; Yao J(姚婧); Cao CW(曹春伟); Luo AL(罗霭玲); Qi M(祁蒙); Wang XL(王宪龙); Wang X(王霄); Huang JJ(黄娇娇); Zhang Y(张颖); Zhang HY(张洪勇); Wang DY(王大愚); Hai-Tao Shang; Hong QL(洪潜龙); Zhang R(张蕊); Jia QT(贾启涛); Zheng QT(郑千涛); Qin GS(秦国嵩); Yong-Shun Li; Tao Zhang; Wei-Wu Jin; Zheng-Yi Chen; Wang HM(王红梅); Zhou Q(周琪); Meng AM(孟安明); Wei H(魏泓); Yang SM(杨仕明); Zhao JG(赵建国)
Adobe PDF(5009Kb) | 收藏 | 浏览/下载：645/190 | 提交时间：2018/07/09 |
